2 Cases of small cell carcinomas with elevation of serum neuron-specific enolase.
نویسندگان
چکیده
منابع مشابه
Neuron specific enolase-positive breast carcinomas.
Ninety-eight patients treated for breast carcinomas were followed from 54 to 75 months after primary diagnosis. All had undergone a modified radical mastectomy with removal of axillary lymph nodes. 36 breast carcinomas were NSE-positive and 62 were negative. NSE-positive tumours were significantly more frequently estrogen receptor-positive than the NSE-negative tumours, and the estrogen recepto...
متن کاملExpression of cytokeratin and neuron-specific enolase in small cell carcinomas of the lung.
Using a polyclonal antibody against human epidermal keratins and a monoclonal antibody against cytokeratins characteristic of simple epithelia, and the Avidin-Biotin system of immunohistochemistry, we have demonstrated cytokeratin expression in 46% and in 60% of small cell carcinomas of the lung at autopsy respectively. The latter gave a diffuse stronger reaction product than the polyclonal ant...
متن کاملPotential utility of serum neuron-specific enolase levels in small cell carcinoma of the lung.
To assess the value of neuron-specific enolase (NSE) as a possible biomarker of small cell lung cancer, serum levels were determined by radioimmunoassay in 93 newly diagnosed untreated patients and were compared to the NSE levels of 20 healthy adult controls [9.6 +/- 0.7 (S.E.) ng/ml]. Serum NSE was elevated (greater than 20 ng/ml) in 73% of all patients including 23 of 39 (59%) with limited-st...
متن کاملRapid electrophoretic determination of neuron-specific enolase isoenzymes in serum.
This assay procedure for each of the two neuron-specific enolases (alpha gamma and gamma gamma) and the non-neuronal enolase (alpha alpha) in serum involves two steps: electrophoretic separation of the three isoenzymes--alpha alpha, alpha gamma, and gamma gamma--on cellulose acetate, and bioluminescence measurement of total enolase activity. From these data, the activity concentrations (U/L) of...
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ژورنال
عنوان ژورنال: Haigan
سال: 1986
ISSN: 1348-9992,0386-9628
DOI: 10.2482/haigan.26.91